Hypothyroxinaemia and Brain Development

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Hypothyroxinaemia and Brain Development

*Correspondence to: John H Lazarus MD, Thyroid Research Group, Cardiff School of Medicine, Cardiff, United Kingdom, E-mail: [email protected] Abstract The aim of this review is to indicate the current position on the role of thyroxine (T4) and fetal brain development with particular relevance to the human situation. Adequate maternal iodine nutrition and maternal circulating thyroxine (T4) conce...

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Maternal hypothyroxinaemia during early pregnancy and subsequent child development: a 3-year follow-up study.

OBJECTIVE To evaluate the impact of maternal hypothyroxinaemia during early gestation (fT4 below the lowest tenth percentile and TSH within the reference range: 0.15-2.0 mIU/l) on infant development, together with any subsequent changes in fT4 during gestation. DESIGN A prospective 3-year follow-up study of pregnant women and their children up to the age of 2 years. MEASUREMENTS Child devel...

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Syntactic Development of Right-Brain and Left-Brain Dominant Iranian EFL Learners: Processability Theory in Perspective

Processability Theory, a component of the cognitive approach to second language acquisition tries to enhance understanding of how the interlanguage knowledge systems can be restructured by second language learners (Pienemann, 1998, 2015). The present study intended to run a similar investigation into the syntactic development of Right-Brain and Left-Brain Dominant Iranian EFL learners based on ...

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Frequency of transient hypothyroxinaemia in low birthweight infants

Thyroid function was studied in 54 low birthweight infants during a 3-week period. Each infant was placed in one of three groups. Group 1 (n = 21), infants who were well and appropriately grown for gestational age; group 2 (n = 23), infants who were appropriately grown but who had hyaline membrane disease; group 3 (n = 10), infants who were small forgestational-age. In group 1, 5 (24 %) infants...

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Transient hypothyroxinaemia associated with developmental delay in very preterm infants.

In 563 surviving very preterm (less than 32 weeks gestational age) and/or very low birthweight (less than 1500 g) infants the relationship between neonatal thyroxine concentration and psychomotor development at 2 years of age (corrected for preterm birth) was studied. A significant association was found between low neonatal thyroxine concentration and a negative score on the three milestones of...

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ژورنال

عنوان ژورنال: Acta Endocrinologica (Bucharest)

سال: 2016

ISSN: 1841-0987,1843-066X

DOI: 10.4183/aeb.2016.1